Tuesday, December 20, 2016

Breathing arrests naloxone vs Hydergine

 Because of "spiked" fentanyl in opiates, deaths among opiate drug users  have now reached epidemic numbers in Canada- in spite of the  effective antidote drug nalaxone.  Two  factors are mainly responsible   viz the opiate addicts are playing a game of "Russian Roulette" because they do not know which opiate is "spiked " with fentanyl. Also because fentanyl even in very low concentrations causes  respiratory arrest and cerebral anoxia  in a time window of less than 10 minutes
 Because in cerebral anoxia - regardless of its etiology- you only have  that short 8-10 min window to avoid the clinical effects of oxygen deprivation (brain death  ).
 In an earlier post on this blog (docsamBlog) I commented (referenced)  that  surgeons  in  many European countries routinely gave hydergine  to their patients (see reference in publication by Life Extension Foundation  entitled "The physicians guide to Life Extension Drugs ) before they begin any major surgical procedure just in case these patients experience a major medical complication like cardiac arrest, fall in blood pressure, etc.  during the operation- thus giving the doctors more time to treat these complications . Using this reasoning  then why not use the same protective approach, i.e.having the opiate drug users take and/or prescribe  hydergine before  the opiate is ingested-  basically having the opiate addicts on hydergine. Incidentally  hydergine is also available by injection giving its protective benefits immediately if the naloxone is not available.
Note: In editing this and other  recent posts on this topic I had mentioned erroneously that narcaine   was the antidote for these respiratory  arrests from opiates. This is an error it should be naloxone . On a google followup  a few days later I note that a drug product called Narcan behaves similarly to naloxone.  
 With the recent deaths of over a dozen addicts in a single day in Vancouver, has anyone considered   doing  tracheostomies  and mechanically assisted breathing  ?

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